Signal Transduction Reagents and Kits

Thermo Scientific Chemicals U-0521, 98%

CAS: 5466-89-7 Molecular Formula: C10H12O3,C10H12O3 Synonym: 3',4'-Dihydroxy-2-methylpropiophenone;

Thermo Scientific Chemicals p21-Activated Kinase Inhibitor III, IPA-3

CAS: 42521-82-4 Molecular Formula: C₂₀H₁₄O₂S₂,C20H14O2S2 Synonym: PAK Inhibitor III; 1,1′-Disulfanediylbis(naphthalen-2-ol)

Thermo Scientific Chemicals Z-Leu-Glu(OMe)-His-Asp(OMe)-fluoromethyl ketone trifluoroacetate salt hydrate

Thermo Scientific Chemicals RITA, p53 activator III

CAS: 213261-59-7 Molecular Formula: C₁₄H₁₂O₃S₂,C14H12O3S2 Synonym: 5,5′-(2,5-Furandiyl)bis-2-thiophenemethanol; NSC 652287

Thermo Scientific Chemicals DNA Methyltransferase Inhibitor

CAS: 48208-26-0 Molecular Formula: C₁₉H₁₄N₂O₄,C19H14N2O4 Molecular Weight (g/mol): 334.33 InChI Key: HPTXLHAHLXOAKV-UHFFFAOYNA-N Synonym: RG108; N-Phthalyl-L-tryptophan IUPAC Name: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-3-(1H-indol-3-yl)propanoic acid SMILES: OC(=O)C(CC1=CNC2=CC=CC=C12)N1C(=O)C2=CC=CC=C2C1=O

Thermo Scientific Chemicals Calpain Inhibitor III, 95+%

CAS: 88191-84-8 Molecular Formula: C₁₉H₃₅N₃O₄S,C22H26N2O4 Molecular Weight (g/mol): 382.46 InChI Key: NGBKFLTYGSREKK-PMACEKPBSA-N Synonym: MDL; Z-Val-Phe-CHO IUPAC Name: benzyl N-[(1S)-2-methyl-1-{[(2S)-1-oxo-3-phenylpropan-2-yl]carbamoyl}propyl]carbamate SMILES: CC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C=O

Thermo Scientific Chemicals 2-Methyl-5-hydroxytryptamine hydrochloride, 97%, Thermo Scientific™

MilliporeSigma™ Simplicon™ RNA Reprogramming Kit (OKSG)

For use as transfection reagent.

Thermo Scientific Chemicals Yohimbine hydrochloride, 98+%

CAS: 65-19-0 Molecular Formula: C₂₁H₂₆N₂O₃·HCl,C21H27ClN2O3 Molecular Weight (g/mol): 390.91 InChI Key: PIPZGJSEDRMUAW-VJDCAHTMSA-N Synonym: 17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride IUPAC Name: hydrogen methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0²,¹⁰.0⁴,⁹.0¹⁵,²⁰]henicosa-2(10),4,6,8-tetraene-19-carboxylate chloride SMILES: [H+].[Cl-].COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCC4=C(NC5=CC=CC=C45)[C@@H]3C[C@H]12

Thermo Scientific Chemicals Calpain Inhibitor I, 95+%

CAS: 110044-82-1 Molecular Formula: C20H37N3O4,C20H37N3O4 Molecular Weight (g/mol): 383.53 InChI Key: FMYKJLXRRQTBOR-BZSNNMDCSA-N Synonym: Ac-LLnL-CHO; ALLN IUPAC Name: (2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-4-methyl-N-[(2S)-1-oxohexan-2-yl]pentanamide SMILES: CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C=O

Thermo Scientific Chemicals Terfenadine

CAS: 50679-08-8 Molecular Formula: C₃₂H₄₁NO₂

Thermo Scientific Chemicals Sulindac Sulfide

CAS: 32004-67-4 Molecular Formula: C₂₀H₁₇FO₂S,C20H17FO2S Molecular Weight (g/mol): 340.41 MDL Number: MFCD00869764 InChI Key: LFWHFZJPXXOYNR-RQZCQDPDSA-N IUPAC Name: 2-[(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfanyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid SMILES: CSC1=CC=C(\C=C2/C(C)=C(CC(O)=O)C3=CC(F)=CC=C23)C=C1

Thermo Scientific Chemicals Calmidazolium Chloride

CAS: 57265-65-3 Molecular Formula: C31H23Cl7N2O,C31H24Cl7N2O Molecular Weight (g/mol): 688.70 InChI Key: LBFGPQFQXRJXDI-UHFFFAOYNA-N IUPAC Name: 1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-2,3-dihydro-1H-imidazole hydrochloridyl SMILES: [Cl].ClC1=CC=C(C=C1)C(N1CN(CC(OCC2=CC=C(Cl)C=C2Cl)C2=CC=C(Cl)C=C2Cl)C=C1)C1=CC=C(Cl)C=C1

Thermo Scientific Chemicals gamma-Secretase Inhibitor I

CAS: 133407-83-7 Molecular Formula: C26H41N3O5,C26H41N3O5 Molecular Weight (g/mol): 475.63 InChI Key: RNPDUXVFGTULLP-UHFFFAOYNA-N Synonym: Z-Leu-Leu-Nle-CHO (Nle = Norleucine); IUPAC Name: benzyl N-[3-methyl-1-({3-methyl-1-[(1-oxohexan-2-yl)carbamoyl]butyl}carbamoyl)butyl]carbamate SMILES: CCCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1)C=O

Thermo Scientific Chemicals Lck Inhibitor II

CAS: 918870-43-6 Molecular Formula: C24H26N6O3 Synonym: 3-(2-(1H-Benzo[d]imidazol-1-yl)-6-(2-morpholinoethoxy)-pyrimidin-4-ylamino)-4-methylphenol;